Selected Publications
Enlund S, Lim C, Amor A, Thomsson C, Sinha I, Fard S, Nilsson A, Hermanson O, Jiang Q*, and Holm F*. Uncovering a role of METTL13 in malignant transformation of hematopoietic stem cells and in the progression of pediatric leukemia. Cell Death & Disease. 2026. * co-corresponding author. PMCID: PMC13243463
Rivera M,Liu L, Enlund S, Lim CE, Zhang H, Yang K, Sasik R, Crews L, Fisch KM, Eskander R, Holm F, Jiang Q. APOBEC3B enhances the efficacy of PARP inhibitors in elimination of ovarian cancer stem cell. Scientific Reports. 2026. PMID: 41535339 PMCID: PMC12881425 DOI: 10.1038/s41598-026-35939-y
Huang M, Mark A, Pham J, Vera K, Saravia-Butler A, Beheshti A, Jiang Q, Fisch K. RNA editing regulates host immune response and T cell homeostasis in SARS-CoV-2 infection. PLoS One. 2024 Aug 23;19(8):e0307450. PMID: 39178184
Rivera M, Lim C, and Jiang Q. An in vitro co-culture assay for rapid expansion of human T-cell acute lymphoblastic leukemia. STAR Proto. 2024 Jun 21;5(2):103103. PMID: 38829737
Rivera M, Zhang H, Pham J, Isquith J, Zhou Q, Sasik R, Mark A, Ma W, Holm F, Fisch K, Kuo D, Jamieson C, Jiang Q. ADAR1 drives stemness of leukemia initiating cells in T-cell acute lymphoblastic leukemia via attenuating immunogenic dsRNA sensing. Cell Reports, 2024. Jan 23;43(2):113704. PMID: 38265938. https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00032-9
Enlund S, Sinha I, Neofytou C, Amor AR, Papadakis K, Nilsson A, Jiang Q, Hermanson O, and Holm F. The CNS Microenvironment Promotes Leukemia Cell Survival by Disrupting Tumor Suppression and Cell Cycle Regulation in Pediatric T-cell Acute Lymphoblastic Leukemia. Experimental Cell Research. https://pubmed.ncbi.nlm.nih.gov/38561062/
Enlund S, Sinha I, Amor AR, Fard S, Tamm E, Jiang Q, Lundin V, Nilsson A, Holm F. Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia. eJHaem. 2023; 4:115-124. https://doi.org/10.1002/jha2.634. https://pubmed.ncbi.nlm.nih.gov/36819185/
Crews L, Ma W, Ladel L, Pham J, Balaian L, Steel K, Mondala P, Diep R, Wu C, Mason C, van der Werf I, Oliver I, Reynoso E, Pineda G, Whisenant T, Wentworth P, La Clair J, Jiang Q, Burkart M, and Jamieson C. Reversal of malignant ADAR1 splice isoform switching with Rebecsinib. Cell Stem Cell, 2023 Mar 2;30(3):250-263. PMCID: PMC10134781. https://pubmed.ncbi.nlm.nih.gov/36803553/
Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, He Y, Mondala Phoebe, Oliver I, Pham J, Ma W, Reynoso E, Ali S, Morris Isabella, Diep R, Nasamran C, Xu G, Sasik R, Rosenthal S, Birmingham A, Coso S, Pineda G, Crews L, Donohoe M, Venter J, Whisenant T, Mesa R, Alexandrov L, Fisch K, Jamieson CH. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Reports. 2021 Jan 26; 34 (4), 108670. PMCID: 33503434. https://pubmed.ncbi.nlm.nih.gov/33503434/
Jiang Q, Isquith J, Zipeto MA, Diep R, Pham J, Santos ND, Reymoso E, Chau J, Leu H, Lazzari E, Melese E, Ma W, Fang R, Minden M, Morris S, Ren B, Pineda G, Holm F, Jamieson CH. Hyper-editing of cell cycle regulatory and tumor suppressor RNA promotes malignant progenitor propagation. Cancer Cell. 2019; 35, 1-4. https://pubmed.ncbi.nlm.nih.gov/30612940/
Zipeto M, Court A, Sadarangani A, Delos-Santos N, Balaian L, Chun H, Pineda G, Morris S, Mason C, Geron I, Barrett C, Goff D, Wall R, Pellecchia M, Minden M, Frazer K, Marra M, Crews L, Jiang Q*, and Jamieson C*. ADAR1 activation drives leukemia stem cell self-renewal by impairing let-7 biogenesis. Cell Stem Cell. 2016, June 7th. PMCID: PMC27292188. * co-corresponding author
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